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Lung cancer patients who quit smoking double their chances of survival

By Staff reporter

Last updated 2/17/2010 5:04:03 PM

Lung cancer patients who quit smoking double their chances of survival

Patients who are diagnosed with early stage lung cancer can double their chances of survival over five years if they stop smoking compared with those who continue to smoke, according to researchers at the University of Birmingham.

There is an established link between smoking and lung cancer; indeed lifelong smokers have a 20-fold increased risk compared with non-smokers. However, until now scientists have not known if cessation on diagnosis can improve prognosis.

Researchers undertook what they describe as the first ever review of studies that measure the effects of continued smoking after diagnosis of lung cancer.

Amanda Parsons, Research fellow at the University of Birmingham, explained: "We found that people who continued to smoke after a diagnosis of early stage lung cancer had a substantially higher risk of death and a greater risk of the tumour returning compared with those who stopped smoking at that time. The data suggests that most of the increased risk of death was due to cancer progression.

The team found that about twice as many quitters would survive for five years compared with continuing smokers, with a five year survival rate of 63-70% among quitters compared with 29-33% among those who continued to smoke.

Amanda added: "The key message here is that it is never too late to give up smoking, benefits can be seen even when you have been diagnosed with lung cancer. Our review suggests that continued smoking may affect the behaviour of a lung tumour and that smoking cessation for those with early stage lung cancer can make a real impact on survival rates.  The next goal for our research is to test the effect of a smoking cessation intervention in this population in a large scale clinical trial. "

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